1 Example of subject 01-001

1.1 Whole images

Let’s start by looking at the entire images. The lesion is only a very small part of it.

2 Preliminary analysis

The current plan is to study the correlation between scans within a specific area. Right now, I will use the area that is labeled as positive in both scans.

Taking one subject as an example:

  1. first pick out pixels that is labeled positive in either scan.
  2. Because scan across sites are so different in scale, let’s standardize them.
  3. Calulate pearson correlation between scans from the same subject at the same site

2.1 Cross-scan regression

  • Regress the second scan on the first scan at given site of the same subject

The range of the Hopkins scans seem to be much larger than the other sites.

3 Cross-site regression

Regress one site on another site (pairwise) at given scan of the same subject.

But how can we do this? Scans at different sites does not have the same one-to-one relationship across voxels. Instead of the relationship between two matrices, this is more like testing the relationship between two distribution.

Below is the distribution of standardized scan: